Oral squamous cell carcinoma diagnosed from saliva metabolic profiling

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Saliva proteome profiling reveals potential salivary biomarkers for detection of oral cavity squamous cell carcinoma.

Oral cavity squamous cell carcinoma (OSCC), which is frequently associated with poor prognosis and mortality, is a leading cause of cancer-related death worldwide. Discovery of body fluid accessible biomarkers is needed to improve OSCC screening. To this end, we profiled proteomes of saliva from the healthy volunteers, the individuals with oral potentially malignant disorders (OPMD), and the OS...

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ژورنال

عنوان ژورنال: Proceedings of the National Academy of Sciences

سال: 2020

ISSN: 0027-8424,1091-6490

DOI: 10.1073/pnas.2001395117